Aptamer-based Biosensor

Aptamers are short single-stranded DNA or RNA molecules capable of binding with precision to a wide range of targets, including proteins, small molecules, and even complex structures such as viruses and cells. They have been shown to possess immense potential in replacing antibodies for the development of new biosensors, diagnostics, and therapeutics. The discovery of aptamers is a critical process as its identification will lead to cost-effective production and scalability that can easily service the needs of any industry.

Our assay development branch, CytoGroup, offers Aptamer selection service that leverages our expertise to assist you in developing aptamers tailored to your specific research or commercial needs. This service is designed to provide you with aptamers that meet stringent criteria, whether you require a high-affinity binding molecule for a therapeutic application, a specific recognition element for a diagnostic test, or a versatile tool for targeted drug delivery. Learn more about Aptamer Selection Service.

 

Optimization Services: Unlock the Full Potential of Your Aptamers

If you already have an aptamer, CytoGroup's optimization services are designed to refine and enhance the specificity, affinity, and stability of your aptamers. Through a comprehensive suite of techniques, including sequence modification, chemical modification, and truncation analysis, we fine-tune your aptamers for superior performance in your applications.

Seamless Assay Development with Your Aptamers

Integrating aptamers into diagnostic platforms can be challenging, but our team has the expertise to do it effectively.

Our integration services are tailored to incorporate your aptamers into a variety of advanced diagnostic and analytical platforms. We are equipped to handle:

  • Lateral Flow Assays (LFAs): We can adapt your aptamers for point-of-care testing, creating rapid, user-friendly, and cost-effective LFAs suitable for a wide range of applications.
  • Enzyme-Linked Immunosorbent Assays (ELISAs): Utilize the high specificity and affinity of aptamers to develop sensitive and quantitative ELISA kits, providing an alternative to traditional antibody-based assays.
  • Surface Plasmon Resonance (SPR): Our team can integrate your aptamers into SPR systems, enabling real-time, label-free analysis of biomolecular interactions with high precision and sensitivity.
  • Aggregation Assays: Aptamers can be used to induce or inhibit aggregation in various assays, providing a unique approach for the detection and quantification of target molecules.
  • Raman Spectroscopy: By coupling your aptamers with Raman spectroscopy, we can develop highly specific and sensitive diagnostic tools for the detection of a wide array of biomolecules.

Leveraging these sophisticated techniques, your aptamers can be transformed into powerful tools for diagnostics, research, and therapeutics.  Learn more at CytoGroup.